Yes, it was indeed a poor sentence, written in haste! What I meant was that presumably, those people who were blogging those concerns were probably mostly mollified by assurances from regulators and governments that the substance was broken down in the arm.
Of course, many of us realized full well that this was not true, and never could have been true. So my question was, I wonder how they felt when they realized that what they had been told was a lie. Probably the most crucial lie of all, because it is so central to the entire regulatory framework applying to the authorizations.
"The bulky muscles have good vascularity, and therefore the injected drug quickly reaches the systemic circulation and thereafter into the specific region of action, bypassing the first-pass metabolism."
I wonder what that mangled sentence if yours is trying to express.
Yes, it was indeed a poor sentence, written in haste! What I meant was that presumably, those people who were blogging those concerns were probably mostly mollified by assurances from regulators and governments that the substance was broken down in the arm.
Of course, many of us realized full well that this was not true, and never could have been true. So my question was, I wonder how they felt when they realized that what they had been told was a lie. Probably the most crucial lie of all, because it is so central to the entire regulatory framework applying to the authorizations.
It's injected IN ORDER to enter the blood stream and elicit systemic immune responses. That doesn't happen in the arm.
Anything interpreted as some sort of reassurance otherwise would have been a mistaken interpretation.
"The bulky muscles have good vascularity, and therefore the injected drug quickly reaches the systemic circulation and thereafter into the specific region of action, bypassing the first-pass metabolism."
https://www.ncbi.nlm.nih.gov/books/NBK556121/